Pharmaceutical Abstracts

PUBLISHED PAPERS USING THE TA.XT2 FOR PHARMACEUTICAL APPLICATIONS

The following list contains abstracts of papers that have stated the use of the Stable Micro Systems Texture Analysers within the pharmaceutical sector. Each list item starts with the name of the author(s). The papers are NOT the property of Stable Micro Systems so we can not therefore supply copies due to copyright laws, but if you have trouble finding them then please contact us (app.support@stablemicrosystems.com) and we will do our best to put you in touch with the author.

Last updated 5th September 2005

Alginate Raft Systems

JOHNSON, F. A., CRAIG, D. Q. M., MERCER, A. D. & CHAUHAN, S. (1997). The effects of alginate molecular structure and formulation variables on the physical characteristics of alginate raft systems. International Journal of Pharmaceutics, 159, 35-42.

Bacterial Cellulose

CHUNG, Y. & SHYU, Y. (1999). The effects of pH, salt, heating and freezing on the physical properties of bacterial cellulose-nata. International Journal of Food Science and Technology, 34 (1), 23-26.

Bioadhesive Films

MOSS, G. P., WOOLFSON, A. D. & McCAFFERTY, D. F. (1999). Mechanical characterisation of Tetracaine-containing bioadhesive films for percutaneous local anaesthesia. Paper presented at the 18th Pharmaceutical Technology Conference, Utrecht, Holland, April 1999, 44-58.

SCHULTZ, P., THO, I. & KLEINEBUDDE, P. (1997).  A new multiparticulate delayed release system.  Part II: Coating formulation and properties of free films.  Journal of Controlled Release, 47, 191-199.

Biogels

ANDREWS, G., JONES, D. & WOOLFSON, D. (2001). Characterisation of binary drug delivery platforms. Paper presented at 28th International Symposium on Controlled Release of Bioactive Materials, 23-27 June 2001, San Diego, USA.

SKULASON, S., KRISTMUNDSDOTTIR, T. & HOLBROOK, W. P. (2004).  MMP - inhibition; a treatment for oral ulceration.  Paper presented at: Controlled Release Society 31st Annual Meeting, 2004.

Blood Plasma Gels

PARES, D., SAGUER, E., SAURINA, J., SUNOL, J. J. & CARRETERO, C. (1998). Functional properties of heat induced gels from liquid and spray-dried porcine blood plasma as influenced by pH. Journal of Food Science, 63 (6), 958-961.

Bones

RANHOTRA, G. S., GELROTH, J. A. & LEINEN, S. D. (1999). Increase in bone calcification in young rats fed breads highly fortified with calcium. Cereal Chemistry, 76 (3), 325-327.

STYLIANOPOULOUS, C., SALDIVAR, S. O. S. & MACKINNEY, G. A. (2002). Effects of fortification and enrichment of maize tortillas on growth and brain development of rat throughout two generations. Cereal Chemistry, 79 (1), 85-91.

Bone Substitute

IOOSS, P., LE RAY, A.-M., GRIMANDI, G., DACULSI, G. & MERLE, C. (2001). A new injectable bone substitute combining poly (E-caprolactone) microparticles with biphasic calcium phosphate granules. Biomaterials, 22, 2785-2794.

WEISS, P., GAUTHIER, O., BOULER, J.-M., GRIMANDI, G. & DACULSI, G. (1999). Injectable bone substitute using a hydrophilic polymer. Bone, 25 (2), 67S-70S.

Carbopol Organogels

JONES, D. S., WOOLFSON, A. D., BROWN, A. F., COULTER, W. A., MCCLELLAND, C. & IRWIN, C. R. (2000).  Design, characterisation and preliminary clinical evaluation of a novel mucoadhesive topical formulation containing tetracycline for the treatment of peridontal disease.  Journal of Controlled Release, 67, 357-368.

MULDOON, B., JONES, D., WOOLFSON, D. & SANDERSON, D. (2001). Controlled release of Tetracycline from Carbopol organogels. Paper presented at 28th International Symposium on Controlled Release of Bioactive Materials, 23-27 June 2001, San Diego, USA.

Cellulose Films

FROHOFF-HULSMANN, M. A., LIPPOLD, B. C., MCGINITY, J. W. (1999). Aqueous ethyl cellulose dispersion containing plasticizers of different water solubility and hydroxypropyl methyl -cellulose as coating material for diffusion pellets II: properties of sprayed films. European Journal of Pharmaceutics and Biopharmaceutics, 48, 67-75.

Celluloseacetate Films

THO, I., SCHULTZ, P., WAALER, T. & KLEINEBUDDE, P. (1999). Mechanical properties of dry and wet free polymer films. Proceedings of the International Symposium of Controlled Release Bioactive Materials, 26, 1999.

Chitosan Sponges

LAI, H. L., ADU'KHALIL, A. & CRAIG, D. Q. M. (2003).  The preparation and characterisation of drug-loaded alginate and chitosan sponges.  International Journal of Pharmaceutics, 251, 175-181.

LEFFLER, C. C. & MULLER, B. W. (2000).  Influence of the acid type on the physical and drug liberation properties of chitosan-gelatin sponges.  International Journal of Pharmaceutics, 194, 229-237.

Faeces

SMIDT, C. R. (1994). Effects of hydrolyzed and intact psyllium and other dietary fibers on GI-function in cecectomized rats fed liquid diets. Poster presented at 18th Clinical Congress, San Antonio, February, 1994.

Freeze-dried Wafers

BOATENG, J. S., AUFFRET, A. D., HUMPFREY, M. J., MATTHEWS, K. H., STEVENS, H. N. E. & ECCLESTON, G. M. (2003).  Mechanical and dissolution properties of freeze-dried wafers and solvent cast films.  Poster presented at AAPS Annual Meeting, Salt Lake City, Utah, USA 26-30 Oct 2003.

Gel Capsules

HODGES, L. A., STEVENS, H. N. E. & MULLEN, A. B. (2004).  Tensile properties of ethylcellulose coatings of a time-delayed oil-filled capsule.  Paper presented at: Controlled Release Society 31st Annual Meeting, 2004.

KUENTZ, M. & ROTHLISBERGER, D. (2002).  Determination of the optimal amount of water in liquid-fill masses for hard gelatin capsules by means of texture analysis and experimental design.  International Journal of Pharmaceutics, 236, 145-152.

PILLAY, V. & FASSIHI, R. (1999). A new method for dissolution studies of lipid-filled capsules employing Nifedipine as a model drug. Pharmaceutical Research, 16 (2), 334-338.

TORRE, M. L., MAGGI, L., VIGO, D., GALLI, A., BORNAGHI, V., MAFFEO, G. & CONTE, U. (2000).  Controlled release of swine semen encapsulated in calcium alginate beads.  Biomaterials, 21, 1493-1498.

Gel Pellets

PILLAY, V. & FASSIHI, R. (1999). In vitro release modulation from crosslinked pellets for site-specific drug delivery to the gastrointestinal tract: I - Physicochemical characterisation of calcium-alginate, calcium-pectinate and calcium-alginate-pectinate pellets. Journal of Controlled Release, 59, 243-256.

TALUKDER, R. & FASSIHI, R. (1999). Determination of dynamics of hydration by tracking phase transitions within a swelling matrix. Paper presented at AAPS Conference, New Orleans, 1999.

Granules

SIMONS, S. J. R., PEPIN, X. & ROSSETTI, D. (2003).  Predicting granule behavior through micro-mechanistic investigations.  Powder Technology, 72, 463-475.

Hot Melt Extruded Films

REPKA, M. A., PRODDUTURI, S. & STODGHILL, S. P. (2003).  Production and characterization of hot-melt extruded films containing clotrimazole.  Drug development and industrial pharmacy, 29 (7), 757-765.

REPKA, M. A., PRODDUTURI, S. & STODGHILL, S. P. (2001). Bioadhesive and chemical properties of hydroxypropyl cellulose hot-melt extruded films containing Nystatin and Clotrimazole. Poster presented at AAPS Annual Meeting, Denver, Colorado, USA.

Hydro Gels

COVIELLO, T., COLUZZI, G., PALLESCHI, A., GRASSI, M., SANTUCCI, E. & ALHAIQUE, F. (2003).  Structural and rheological characterization of Scleroglucan/borax hydrogel for drug delivery.  Biological Macromolecules, 32, 83-92.

GOUDA, N. & HILDGEN, P. (2004).  Texture profile analysis as a mean to assess mechanical properties of thermoreversible mucoadhesive nasal hydrogels.  Poster presented at Canadian Society for Pharmaceutical Sciences, 7th Annual Symposium, 9-12 June 2004.

IZA, M., STOIANOVICI, G., VIORA, L., GROSSIORD, J. L. & COUARRAZE, G. (1998).  Hydrogels of poly(ethylene glycol): mechanical characterization and release of a model drug.  Journal of Controlled Release, 52, 41-51.

MARTIN, L., WILSON, C. G., KOOSHA, F., & UCHEGBU, I. F. (2003).  Sustained buccal delivery of the hydrophobic drug delivery of the hydrophobic drug denbufylline using physically cross-linked palmitoyl glycol chitosan hydrogels.  European Journal of Pharmaceutics and Biopharmaceutics, 55, 35-45.

MARTIN, L., WILSON, C. G., KOOSHA, F., TETLEY, L., GRAY, A. I., SENEL, S., UCHEGBU, I. F. (2002).  The release of model macromolecules may be controlled by the hydrophobicity of palmitoyl glycol chitosan hydrogels.  Journal of Controlled Release, 80, 87-100.

McCOY, C., GORMAN, S., JONES, D., McLAUGHLIN, D. & ROONEY, C. (2001). Characterisation of partially-biodegradable semi-interpenetrating polymer networks. Paper presented at 28th International Symposium on Controlled Release of Bioactive Materials, 23-27 June 2001, San Diego, USA.

PARK, J. S., PARK, J. W. & RUCKENSTEIN, E. (2001).  Thermal and dynamic mechanical analysis of PVA/MC blend hydrogels.  Polymer, 42, 4271-4280.

SKULASON, S. KRISTMUNDSDOTTIR, T. & HOLBROOK, W. P. (2000). A technique for evaluating the adhesion of hydrogel compositions. Proceedings of the International Symposium of Controlled Release Bioactive Materials, Paris, 11-13 July, 2000.

VERVOORT, L., ROMBAUT, P., VAN DEN MOOTER, G., AUGUSTIJNS, P. & KINGET, R. (1998).  Inulin hydrogels. II. In vitro degradation study.  International Journal of Pharmaceutics, 172, 137-145.

WOOLFSON, A. D., MALCOLM, R. K., CAMPBELL, K., JONES, D. S. & RUSSELL, J. A. (2000).  Rheological, mechanical and membrane penetration properties of novel dual drug systems for percutaneous delivery.  Journal of Controlled Release, 67, 395-408.

Hydroxyethylcellulose Gels

CAMPBELL, K., MALCOLM, R. K., RUSSELL, J. A. & WOOLFSON, A. D. (1999). Rheological behaviour of pharmaceutical gels, suspensions and eutectic emulsions of Ibuprofen and Methyl Nicotinate. Paper presented at the 18th Pharmaceutical Technology Conference, Utrecht, Holland, April 1999, 201-213.

Lactose

LISTIOHADI, Y. D., HOURIGAN, J. A., STEELE, R. J., JOHNSON, R. L. & SLEIGH, R. W. (2002).  Lactose: Polymorphism, caking behaviour and use in pharmaceuticals.  Paper presented at WCPT4 Conference, 21-25 July 2002, Sydney, Australia.

Lozenges

CODD, J. E. & DEASY, P. B. (1998).  Formulation development and in vivo evaluation of a novel bioadhesive lozenge containing a synergistic combination of antifungal agents.  International Journal of Pharmaceutics, 173, 13-24.

Lyophilisates

THAPA, P., STEVENS, H. N. E. & BAILLIE, A. J. (1999). Lyophilised dosage form for the nasal delivery of drugs. Proceedings of the International Symposium of Controlled Release Bioactive Materials, 26, 1999.

Microcapsules

ORIVE, G., HERNANDEZ, R. M., GASCON, A. R., IGARTUA, M. & PEDRAZ, J. L. (2003).  Development and optimisation of alginate-PMCG-alginate microcapsules for cell immobilisation.  International Journal of Pharmaceutics, 259, 57-68.

Methyl Nicotinate Gels

CAMPBELL, K., MALCOLM, R. K., RUSSELL, J. A. & WOOLFSON, A. D. (1999). Rheological behaviour of pharmaceutical gels, suspensions and eutectic emulsions of Ibuprofen and Methyl Nicotinate. Paper presented at the 18th Pharmaceutical Technology Conference, Utrecht, Holland, April 1999, 201-213.

Oral Mucosal Patches

REPKA, M. A., MUNJAL, M., GUTTA, K. & STODGHILL, S. (2001). Physical and chemical properties of transmucosal hydroxypropyl cellulose and hydroxypropyl methylcellulose films containing Lidocaine. Poster presented at AAPS Annual Meeting, Denver, Colorado, USA.

WONG, C. F., YUEN, K. H. & PEH, K. K. (1999).  Formulation and evaluation of controlled release Eudragit buccal patches.  International Journal of Pharmaceutics, 178, 11-22.

Pellets

SIMONS, S. J. R. & PEPIN, X. (2003).  Hardness of moist agglomerates in relation to interparticle friction, capillary and viscous forces.  Powder Technology, 138, 57-62.

STECKEL, H. & MINDERMANN-NOGLY, F. (2003).  Production of chitosan pellets by extrusion/spheronization.  European Journal of Pharmaceutics and Biopharmaceutics, 57, 107-114.

THO, I., SANDE, S. A. & KLEINEBUDDE, P. (2003).  Disintegrating pellets from a water-insoluble pectin derivative produced by extrusion/spheronisation.  European Journal of Pharmaceutics and Biopharmaceutics, 56, 371-380.

Polysaccharide Gels

JONES, D. S., WOOLFSON, A. D. & DJOKIC, J. (1996). Texture profile analysis of bioadhesive polymeric semisolids: Mechanical characterization and investigation of interactions between formulation components. Journal of Applied Polymer Science, 61, 2229-2234.

JONES, D. S., WOOLFSON, A. D., & BROWN, A. F. (1997). Textural, viscoelastic and mucoadhesive properties of pharmaceutical gels composed of cellulose polymers. International Journal of Pharmaceutics, 151, 223-233.

JONES, D. S., WOOLFSON, A. D., BROWN, A. F. & O'NEILL, M. J. (1997). Mucoadhesive, syringeable drug delivery systems for controlled application of metronidazole to the periodontal pocket: In vitro release kinetics, syringeability, mechanical and mucoadhesive properties. Journal of Controlled Release, 49, 71-79.

McTAGGART, L. E. & HALBERT, G. W. (1993). Assessment of Polysaccharide Gels as Drug Delivery Vehicles. International Journal of Pharmaceutics, 100, 199-206.

NIELSEN, L. S., SCHUBERT, L. & HANSEN, J. (1998). Bioadhesive drug delivery systems I. Characterisation of mucoadhesive properties of systems based on glyceryl mono-oleate and glyceryl monolinoleate. European Journal of Pharmaceutical Sciences, 6, 231-239.

TAMBURIC, S. & CRAIG, D. Q. M. (1997). A comparison of different in vitro methods for measuring mucoadhesive performance. European Journal of Pharmaceutics and Biopharmaceutics, 44, 159-167.

TOBYN, M. J., STANIFORTH, J. N., JORGENSEN, E. & BHAGWAT, D. (1997). Use of gel strength analysis to characterise a polysaccharide controlled release matrix. Controlled Release of Bioactive Materials Conference Paper, 1997.

Polymer Gels

HAGERSTROM, H & EDSMAN, K. (2000). A new detachment force method for measuring mucoadhesion of gels intended for nasal administration - comparison with a rheological method. Proceedings of the International Symposium of Controlled Release Bioactive Materials, Paris, 11-13 July, 2000.

Poly(Methyl Vinyl Ether-Maleic Anhydride) gels

LAWLOR, M. S., JONES, D. S. & WOOLFSON, A. D. (1999). Analysis of the mechanical and rheological properties of Tetracycline-containing gels composed of Poly(Methyl Vinyl Ether-Maleic Anhydride) and Polyvinylpyrrolidone. Paper presented at the 18th Pharmaceutical Technology Conference, Utrecht, Holland, April 1999, 306-309.

LAWLOR, M. S., JONES, D. S. & WOOLFSON, A. D. (1999). Rheological and mechanical characterisation of Tetracycline-containing gels designed for the treatment of periodontal diseases. Proceedings of the International Symposium of Controlled Release Bioactive Materials, 26, 1999.

Polyethylene Glycol Gels

TAN, Y. T. F., PEH, K. K. & AL-HANBALI, O. (2000).  Effect of Carbopol and Polyvinylpyrrolidone on the mechanical, rheological, and release properties of bioadhesive Polyethylene Glycol gels.  AAPS PharmSciTech, 1 (3), 24.

Polymer Films

MISSAGHI, S. & FASSIHI, R. (2004).  A novel approach in the assessment of polymeric film formation and film adhesion on different pharmaceutical solid substrates.  Paper presented at: AAPS PharmSciTech 2004.

ZIEGLER, R. & KOLTER, K. (2003).  Protection of light-sensitive active ingredients by instant-release coating based on Kollicoat IR.  Poster presented at AAPS Annual Meeting, Salt Lake City, Utah, USA 26-30 October 2003.

Salivary Replacement Gel

KELLY, H. M., PURCELL, C. H. & DEASY, P. B. (2000). Development of a salivary replacement gel for the symptomatic treatment of xerostomia. Proceedings of the International Symposium of Controlled Release Bioactive Materials, Paris, 11-13 July, 2000.

Silicone Intravaginal Rings

GALLAGHER, R. J., MALCOLM, R. K., RUSSELL, J. A. & WOOLFSON, A. D. (1999). Determination of tensile and compressional properties of silicone intravaginal rings using a modified texture analyser. Paper presented at the 18th Pharmaceutical Technology Conference, Utrecht, Holland, April 1999, 288-297.

Skin Patches (Transdermal Patches)

SHIN, Y. H., LEE, Y. D. & KIM, J. J. (2001). Preparation and evaluation of a Ketorolac transdermal drug delivery system. Paper presented at 28th International Symposium on Controlled Release of Bioactive Materials, 23-27 June 2001, San Diego, USA.

WOOLFSON, A. D., McCAFFERTY, D. F. & MOSS, G. P. (1998).  Development and characterisation of a moisture-activated bioadhesive drug delivery system for percutaneous local anaesthesia.  International Journal of Pharmaceutics, 169, 83-94.

Skin Wounds

BAIE, S. H. & SHEIKH, K. A. (1999). Effect of palm oil based creams containing Channa Striatus (Snake head fish) as an active ingredient on tensile strength of healing wounds in rats. Paper presented at: 18th Pharmaceutical Technology Conference, Utrecht, April, 1999.

Sodium Hyaluronate Gels

HAGERSTROM, H. & EDSMAN, K. (2001). Investigation of bioadhesive properties of linear and cross-linked sodium hyaluronate gels. Poster presented at AAPS Annual Meeting, Denver, Colorado, USA.

Solvent Cast Films

BOATENG, J. S., AUFFRET, A. D., HUMPFREY, M. J., MATTHEWS, K. H., STEVENS, H. N. E. & ECCLESTON, G. M. (2003).  Mechanical and dissolution properties of freeze-dried wafers and solvent cast films.  Poster presented at AAPS Annual Meeting, Salt Lake City, Utah, USA 26-30 Oct 2003.

Sputum

TRAINOR, D. M., BARKER, S. A., CRAIG, D. Q. M. & ELBORN, J. (2002).  The use of texture analysis to assess the physical properties of sputum collected from adult cystic fibrosis patients.  Poster presented at British Pharmaceutical Conference 2002, Manchester, UK.

TRAINOR, D. M., BARKER, S. A., CRAIG, D. Q. M. & ELBORN, J. S. (2002).  The measurement of the physical properties of cystic fibrosis sputum using texture analysis.  Paper presented at North American Cystic Fibrosis Conference 2002.

Tablets

CONTE, U., MAGGI, L., TORRE, M. L., GIUNCHEDI, P. & LA MANNA, A. (1993). Press-coated tablets for time-programmed release of drugs. Biomaterials, 14 (13), 1017-1023.

DAS, S. K. & DAS, N. G. (2004).  Development of mucoadhesive sublingual delivery system for buprenorphine.  Paper presented at: Controlled Release Society 31st Annual Meeting, 2004.

DOR, J. M., CHAU, A., PREVYSH-ROGERS, V., CHU, J. & FIX, J. A. (2000). A new in-vitro method vs the standard USP method to measure the disintegration time of fast-disintegration tablets. Proceedings of the International Symposium of Controlled Release Bioactive Materials, Paris, 11-13 July, 2000.

DOR, P, J. M., FIX, J. A. & JOHNSON, M. I. (1999). A new in-vitro method to measure the disintegration time of a fast-disintegration tablet. Proceedings of the International Symposium of Controlled Release Bioactive Materials, 26, 1999.

LI, A., DAS, S. K. & DAS, N. G. (2003).  Development of mucoadhesive sublingual dosage forms of buprenorphine.  Poster presented at AAPS Annual Meeting, Salt Lake City, Utah, USA 26-30 Oct 2003.

MEYER, K. & KOLTER, K. (2004).  Reliability of drug release from innovative single unit Kollicoat DDS.  Paper presented at: Controlled Release Society 31st Annual Meeting, 2004.

MILLER, R. W., GUPTA, A. (2004).  Roller compaction: A PAT application using near-infrared in-process mapping, monitoring and characterisation.  American Pharmaceutical Review, 69-76, 103.

MILLS, S., TOBYN, M. J. & STANIFORTH, J. N. (2001). Metered dose dermal drug delivery: Pandermal tablets. Poster presented at AAPS Annual Meeting, Denver, Colorado, USA.

OWENS, T. S., DANSEREAU, R. J. & SAKR, A. (2005).  Development and evaluation of extende release bioadhesive sodium flouride tablets.  International Journal of Pharmaceutics, In Press.

PARK, C. R. & MUNDAY, D. L. (2003). Development and evaluation of a biphasic buccal adhesive tablet for nicotine replacement therapy.  International Journal of Pharmaceutics, 237, 215-226.

PILLAY, V. & FASSIHI, R. (1999). Electrolyte-induced compositional heterogeneity: A novel approach for rate-controlled oral drug delivery. Journal of Pharmaceutical Sciences, 88 (11), 1140-1148.

PILLAY, V. & FASSIHI, R. (2000). In situ electrolyte interactions in a disk-compressed configuration system for up-curving and constant drug delivery. Journal of Controlled Release, 67, 55-65.

PILLAY, V., & FASSIHI, R. (2000). A novel approach for constant rate delivery of highly soluble bioactives from a simple monolithic system. Journal of Controlled Release, 67, 67-78.

SOHI, H., KHAR, R. K. & SINGH, S. (2004).  Development of controlled-release taste masked buccal tablets of an anti-migraine agent.  Paper presented at: Controlled Release Society 31st Annual Meeting, 2004.

SUNGTHONGIEEN, S., PUTTIPIPATKACHORN, S., PAERATAKUL, O., DASHEVSKY, A. & BODMEIER, R. (2004).  Effect of plasticizers on behavior of rupturable pulsatile release tablets.  Paper presented at: Controlled Release Society 31st Annual Meeting, 2004.

SURAPANENI, M. S., DAS, N. G. & DAS, S. K. (2003).  Correlation of mucoadhesive force to the concentration of mucoadhesive polymer in formulations.  Poster presented at AAPS Annual Meeting, Salt Lake City, Utah, USA, 26-30 October 2003.

TOBYN, M., JOHNSON, J. R. & GIBSON, S. (1994). Use of a TA.XT2 Texture Analyser in Mucoadhesive Research. International Labmate, Vol. XVII, Issue VI.

TOBYN, M. J., JOHNSON, J. R. & DETTMAR, P. W. (1995). Factors affecting in vitro gastric mucoadhesion I. Test conditions and instrumental parameters. European Journal of Pharmaceutics and Biopharmaceutics, 41 (4), 235-241.

TOBYN, M. J., JOHNSON, J. R. & DETTMAR, P. W. (1996). Factors affecting in vitro gastric mucoadhesion II. Physical properties of polymers. European Journal of Pharmaceutics and Biopharmaceutics, 42 (1), 56-61.

TOBYN, M. J., JOHNSON, J. R. & DETTMAR, P. W. (1997). Factors affecting in vitro gastric mucoadhesion IV. Influence of tablet excipients, surfactants and salts on the observed mucoadhesion of polymers. European Journal of Pharmaceutics and Biopharmaceutics, 43, 65-71.

YANG, L., JOHNSON, B. & FASSIHI, R. (1998). Determination of continuous changes in the gel layer thickness of poly(ethylene oxide) and HPMC tablets undergoing hydration: a texture analysis study. Pharmaceutical Research, 15 (12), 1902-1906.

ZULEGER, S., RASSIHI, R. & LIPPOLD, B. C. (2000). Texture analysis and photomicroscopy to investigate the swelling of controlled release cellulose ether tablets. Paper presented at APV Congress, Berlin, April 2000.

ZULEGER, S., FASSIHI, R., LIPPOLD, B. C. (2002).  Polymer particle erosion controlling drug release: II. Swelling investigations to clarify the release mechanism.  International Journal of Pharmaceutics, 247, 23-37.

Thermosensitive Gels

CHANG, J. Y., OH, Y. K., KONG, H. S., KIM, E. J. & KIM, C. H. (2002).  Prolonged antifungal effects of clotrimazole-containing mucoadhesive thermosensitive gels on candida albicans vaginitis.  Paper presented at Controlled Release Society 29th Annual Meeting,  July 20-25th 2002.